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Our mission is to advance the complex science that underlies the treatment of children and adults with congenital and pediatric acquired heart disease so that we can continuously improve care and patient outcomes. To help meet this goal, the Benderson Family Heart Center maintains an active roster of clinical trials and ongoing research.

Since 1949, Boston Children's has pioneered cardiovascular innovations that have dramatically improved survival rates and the quality of life those born with heart defects. The Benderson Family Heart Center attracts major research support from funding agencies, including the National Institutes of Health and the American Heart Association. We have the nation's largest clinical and basic research program focused on pediatric heart disease, and we are an innovator in translational research — bringing laboratory discoveries to the bedside as quickly as possible.

Clinician looks at molecules in petri dish

Learn about the ongoing Cardiology clinical trials and research labs that are advancing the field forward.

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Recent research and innovation stories

Innovation plays a critical role in our patients' health, so we are constantly creating new ways to treat heart diseases. Our scientists investigate every aspect of the heart and the conditions that affect it, so we can offer new and improved treatments to our patients. Our program's culture is one of innovation — of solving difficult problems that others haven't been able to solve, tackling the most complex cases, and figuring out ways to make the process easier on pediatric and adult patients.

Fetal brain imaging predicts neurodevelopment of babies with congenital heart disease
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"Seeing" the unseen: A way to pinpoint elusive cardiac conduction tissue 
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Clinical trial aims to reduce complications in life-saving lung and heart treatment
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Publications

March 2024
  1. Ajayi O, Alizadeh F, Sekhavat S, Bonello K, Beroukhim RS, Ghelani SJ. Morphology, Clinical Associations, and Pathologic Follow-up of Quadricuspid Aortic Valves in Children. Pediatr Cardiol. 2024. Epub 20240313. doi: 10.1007/s00246-024-03471-3. PubMed PMID: 38478047.
  2. Chubb H, Mah DY, Shah M, Lin KY, Peng DM, Hale BW, May L, Etheridge S, Goodyer W, Ceresnak SR, Motonaga KS, Rosenthal DN, Almond CS, McElhinney DB, Dubin AM. Multicenter Study of Survival Benefit of Cardiac Resynchronization Therapy in Pediatric and Congenital Heart Disease. JACC Clin Electrophysiol. 2024;10(3):539-50. Epub 20240110. doi: 10.1016/j.jacep.2023.11.008. PubMed PMID: 38206260.
  3. Critser PJ, Buchmiller TL, Gauvreau K, Zalieckas JM, Sheils CA, Visner GA, Shafer KM, Chen MH, Mullen MP. Exercise-induced Pulmonary Hypertension in Long-term Survivors of Congenital Diaphragmatic Hernia. J Pediatr. 2024:114034. Epub 20240327. doi: 10.1016/j.jpeds.2024.114034. PubMed PMID: 38552948.
  4. DiLorenzo MP, Lee S, Rathod RH, Raimondi F, Farooqi KM, Jain SS, Samyn MM, Johnson TR, Olivieri LJ, Fogel MA, Lai WW, Renella P, Powell AJ, Buddhe S, Stafford C, Johnson JN, Helbing WA, Pushparajah K, Voges I, Muthurangu V, Miles KG, Greil G, McMahon CJ, Slesnick TC, Fonseca BM, Morris SA, Soslow JH, Grosse-Wortmann L, Beroukhim RS, Grotenhuis HB. Design and implementation of multicenter pediatric and congenital studies with cardiovascular magnetic resonance: Big data in smaller bodies. J Cardiovasc Magn Reson. 2024;26(1):101041. Epub 20240323. doi: 10.1016/j.jocmr.2024.101041. PubMed PMID: 38527706.
  5. Ferraro AM, Harrild DM, Powell AJ, Levy PT, Marx GR. Evolving Role of Three-Dimensional Echocardiography for Right Ventricle Volume Analysis in Pediatric Heart Disease: Literature Review and Clinical Applications. J Am Soc Echocardiogr. 2024. Epub 20240309. doi: 10.1016/j.echo.2024.03.001. PubMed PMID: 38467312.
  6. Kayoum AA, Rivera Flores E, Reyes M, Almasarweh SI, Ojito J, Burke RP, Sasaki J. Safety of bloodless open-heart surgery on cardiopulmonary bypass in selected children: A single center experience with minimal invasive extracorporeal circulation. Perfusion. 2024;39(2):391-8. Epub 20221208. doi: 10.1177/02676591221145623. PubMed PMID: 36482703.
  7. Kim ME, Baskar S, Janson CM, Chandler SF, Whitehill RD, Dionne A, Law MA, Domnina Y, Smith-Parrish MN, Bird GL, Banerjee M, Zhang W, Reichle G, Schumacher KR, Czosek RJ, Morales DLS, Alten JA. Epidemiology of Postoperative Junctional Ectopic Tachycardia in Infants Undergoing Cardiac Surgery. Ann Thorac Surg. 2024. Epub 20240312. doi: 10.1016/j.athoracsur.2024.03.002. PubMed PMID: 38484909.
  8. Klassen SL, Okello E, Ferrer JME, Alizadeh F, Barango P, Chillo P, Chimalizeni Y, Dagnaw WW, Eisele JL, Eberly L, Gomanju A, Gupta N, Koirala B, Kpodonu J, Kwan G, Mailosi BGD, Mbau L, Mutagaywa R, Pfaff C, Pinero D, Pinto F, Rusingiza E, Sanni UA, Sanyahumbi A, Shakya U, Sharma SK, Sherpa K, Sinabulya I, Wroe EB, Bukhman G, Mocumbi A. Decentralization and Integration of Advanced Cardiac Care for the World's Poorest Billion Through the PEN-Plus Strategy for Severe Chronic Non-Communicable Disease. Glob Heart. 2024;19(1):33. Epub 20240327. doi: 10.5334/gh.1313. PubMed PMID: 38549727; PubMed Central PMCID: PMCPMC10976983.
  9. Kumar SR, Gaynor JW, Heuerman H, Mayer JE, Jr., Nathan M, O'Brien JE, Jr., Pizarro C, Subacius H, Wacker L, Wellnitz C, Eghtesady P. The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2023 Update on Outcomes and Research. Ann Thorac Surg. 2024. Epub 20240322. doi: 10.1016/j.athoracsur.2024.03.018. PubMed PMID: 38522772.
  10. McGeoghegan P, Lu M, Sleeper LA, Emani S, Baird C, Feins E, Gellis LA, Friedman KG. Cleft closure and other predictors of contemporary outcomes after atrioventricular canal repair in patients with parachute left atrioventricular valve. Interdiscip Cardiovasc Thorac Surg. 2024. Epub 20240327. doi: 10.1093/icvts/ivae048. PubMed PMID: 38539038.
  11. Niebler RA, Shezad M, Absi M, Aljohani OA, Amdani S, Auerbach S, Bearl DW, Boucek K, Buchholz H, Castleberry C, Dykes J, Engelhardt K, Friedland-Little J, Hope K, Iqbal M, Jeewa A, Joong A, Lorts A, May L, Mokshagundam D, Nandi D, O'Connor M, Parent JJ, Peng DM, Shwaish N, Shugh SB, VanderPluym C, Vaughn G, Zinn M. Impact of HeartWare ventricular assist device discontinuation on the pediatric population: An Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry analysis. JHLT Open. 2024;4:100064. doi: [2]https://doi.org/10.1016/j.jhlto.2024.100064.
  12. Pan X, Tao AM, Lu S, Ma M, Hannan SB, Slaugh R, Drewes Williams S, O'Grady L, Kanca O, Person R, Carter MT, Platzer K, Schnabel F, Abou Jamra R, Roberts AE, Newburger JW, Revah-Politi A, Granadillo JL, Stegmann APA, Sinnema M, Accogli A, Salpietro V, Capra V, Ghaloul-Gonzalez L, Brueckner M, Simon MEH, Sweetser DA, Glinton KE, Kirk SE, Baylor College of Medicine Center for Precision Medicine M, Wangler MF, Yamamoto S, Chung WK, Bellen HJ. De novo variants in FRYL are associated with developmental delay, intellectual disability, and dysmorphic features. Am J Hum Genet. 2024. Epub 20240306. doi: 10.1016/j.ajhg.2024.02.007. PubMed PMID: 38479391.
  13. Przybylski R, Meziab O, Gauvreau K, Dionne A, DeWitt ES, Bezzerides VJ, Abrams DJ. Premature ventricular contractions in children and young adults: natural history and clinical implications. Europace. 2024;26(3). doi: 10.1093/europace/euae052. PubMed PMID: 38441283; PubMed Central PMCID: PMCPMC10927167.
  14. Roy N, Parra MF, Brown ML, Sleeper LA, Kossowsky J, Baumer AM, Blitz SE, Booth JM, Higgins CE, Nasr VG, Del Nido PJ, Brusseau R. Erector Spinae Blocks for opioid-sparing multimodal pain management after Pediatric Cardiac Surgery. J Thorac Cardiovasc Surg. 2024. Epub 20240315. doi: 10.1016/j.jtcvs.2024.03.010. PubMed PMID: 38493959.
  15. Sedghi A, Kaiser DPO, Cuberi A, Schreckenbauer S, Wojciechowski C, Friehs I, Reichmann H, Barlinn J, Barlinn K, Puetz V, Siepmann T. Intravenous Thrombolysis Before Thrombectomy Improves Functional Outcome After Stroke Independent of Reperfusion Grade. J Am Heart Assoc. 2024;13(6):e031854. Epub 20240308. doi: 10.1161/JAHA.123.031854. PubMed PMID: 38456409.
  16. Sperotto F, Alexander PMA, MacLaren G. Extracorporeal Cardiopulmonary Resuscitation in Children With Primary Noncardiac Diagnoses: Untangling a Complex Intervention. Crit Care Med. 2024;52(4):663-5. Epub 20240314. doi: 10.1097/CCM.0000000000006204. PubMed PMID: 38483222.
February 2024
  1. Chen J, Zhang X, DeLaughter DM, Trembley MA, Saifee S, Xiao F, Chen J, Zhou P, Seidman CE, Seidman JG, Pu WT. Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution. Circ Res. 2024;134(5):529-46. Epub 20240213. doi: 10.1161/CIRCRESAHA.123.323956. PubMed PMID: 38348657; PubMed Central PMCID: PMCPMC10906678.
  2. de Sousa E, de Mendonca M, Bolin AP, de Oliveira NP, Real CC, Hu X, Huang ZP, Wang DZ, Rodrigues AC. Sex-specific regulation of miR-22 and ERalpha in white adipose tissue of obese dam's female offspring impairs the early postnatal development of functional beige adipocytes in mice. Biochim Biophys Acta Mol Basis Dis. 2024;1870(4):167057. Epub 20240207. doi: 10.1016/j.bbadis.2024.167057. PubMed PMID: 38331111.
  3. Fernandez-Cisneros A, Staffa SJ, Emani SM, Chavez M, Friedman KG, Hoganson DM, Kaza AK, Del Nido PJ, Baird CW. Association of tetralogy of Fallot and complete atrioventricular canal: a single-centre 40-year experience. Eur J Cardiothorac Surg. 2024;65(2). doi: 10.1093/ejcts/ezae037. PubMed PMID: 38310341.
  4. Foster SN, Best K, Tumin D, Li X, Desher K, Thiagarajan RR, Raman L. Survival and Neurobehavioral Outcomes Following Out-of-Hospital Cardiac Arrest in Pediatric Patients with Pre-Existing Morbidity: An Analysis of the THAPCA Out-of-Hospital Arrest Data. Resuscitation. 2024:110144. Epub 20240215. doi: 10.1016/j.resuscitation.2024.110144. PubMed PMID: 38367829.
  5. Frank LH, Glickstein J, Brown DW, Mink RB, Ross RD. Child Health Needs and the Pediatric Cardiology Workforce: 2020-2040. Pediatrics. 2024;153(Suppl 2). doi: 10.1542/peds.2023-063678E. PubMed PMID: 38300014; PubMed Central PMCID: PMCPMC10852197.
  6. Geanacopoulos AT, Zielonka B, Fox MT, Kerr S, Chambers KD, Przybylski R, Burns MM. Pediatric antiarrhythmics and toxicity: A clinical review. J Am Coll Emerg Physicians Open. 2024;5(1):e13090. Epub 20240215. doi: 10.1002/emp2.13090. PubMed PMID: 38371660; PubMed Central PMCID: PMCPMC10869663.
  7. Jacquemyn X, Singh TP, Gossett JG, Averin K, Kutty S, Zuhlke LJ, Abdullahi LH, Kulkarni A. Mortality and Heart Transplantation After Hybrid Palliation of Hypoplastic Left Heart Syndrome: A Systematic Review and Meta-Analysis. World J Pediatr Congenit Heart Surg. 2024:21501351231224323. Epub 20240225. doi: 10.1177/21501351231224323. PubMed PMID: 38404131.
  8. Knapp WP, O'Leary ET, Quinn B, Porras D, Mah DY. Safety and efficacy of combined dilation/stenting of venous abnormalities, including complete obstructions, during lead extractions in patients with congenital heart disease. J Cardiovasc Electrophysiol. 2024. Epub 20240208. doi: 10.1111/jce.16202. PubMed PMID: 38332493.
  9. Liddle D, Gearhart A, Sleeper LA, Lu M, Feins E, Schidlow DN, Ghelani S, Powell AJ, Emani S, Beroukhim RS. Mitral Valve Orifice Area Predicts Outcome after Biventricular Repair in Patients with Hypoplastic Left Ventricles. J Cardiovasc Magn Reson. 2024:101029. Epub 20240223. doi: 10.1016/j.jocmr.2024.101029. PubMed PMID: 38403073.
  10. Lopez L, Saurers DL, Barker PCA, Cohen MS, Colan SD, Dwyer J, Forsha D, Friedberg MK, Lai WW, Printz BF, Sachdeva R, Soni-Patel NR, Truong DT, Young LT, Altman CA. Guidelines for Performing a Comprehensive Pediatric Transthoracic Echocardiogram: Recommendations From the American Society of Echocardiography. J Am Soc Echocardiogr. 2024;37(2):119-70. doi: 10.1016/j.echo.2023.11.015. PubMed PMID: 38309834.
  11. Mah DY. Wearable technology for heart rhythm monitoring in children. Heart Rhythm. 2024. Epub 20240206. doi: 10.1016/j.hrthm.2024.02.003. PubMed PMID: 38331305.
  12. Mayourian J, La Cava WG, Vaid A, Nadkarni GN, Ghelani SJ, Mannix R, Geva T, Dionne A, Alexander ME, Duong SQ, Triedman JK. Pediatric ECG-Based Deep Learning to Predict Left Ventricular Dysfunction and Remodeling. Circulation. 2024. Epub 20240205. doi: 10.1161/CIRCULATIONAHA.123.067750. PubMed PMID: 38314583.
  13. Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernandez B, Asch FM, Barker AJ, Sierra LM, de Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, de Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schafers HJ. [Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes]. Arch Cardiol Mex. 2024. Epub 20240207. doi: 10.24875/ACM.24000002. PubMed PMID: 38325117.
  14. Milligan C, Williams RJ, Singh TP, Bastardi HJ, Esteso P, Almond CSD, Gauvreau K, Daly KP. Impact of a Positive Crossmatch on Pediatric Heart Transplant Outcomes. J Heart Lung Transplant. 2024. Epub 20240227. doi: 10.1016/j.healun.2024.02.1457. PubMed PMID: 38423415.
  15. Ortinau CM, Newburger JW. Placenta-Heart-Brain Connection in Congenital Heart Disease. J Am Heart Assoc. 2024:e033875. Epub 20240229. doi: 10.1161/JAHA.124.033875. PubMed PMID: 38420776.
  16. Pasquali SK, O'Brien SM, Shahian DM, Romano JC, Jacobs JP, Mayer JE. Association Between Past and Present Operative Mortality in Congenital Heart Surgery. Ann Thorac Surg. 2024. Epub 20240222. doi: 10.1016/j.athoracsur.2024.02.018. PubMed PMID: 38401767.
  17. Prondzynski M, Pioner JM, Sala L, Bellin M, Meraviglia V. Editorial: Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications. Front Physiol. 2024;15:1378495. Epub 20240219. doi: 10.3389/fphys.2024.1378495. PubMed PMID: 38440346; PubMed Central PMCID: PMCPMC10910021.
  18. Ramdat Misier NL, Moore J, Nguyen HH, Lloyd MS, Dubin AM, Mah DY, Czosek RJ, Khairy P, Chang PM, Nielsen JC, Aydin A, Pilcher TA, O'Leary ET, Shivkumar K, de Groot NMS. Long-Term Outcomes of Cardiac Resynchronization Therapy in Patients With Repaired Tetralogy of Fallot: A Multicenter Study. Circ Arrhythm Electrophysiol. 2024:e012363. Epub 20240212. doi: 10.1161/CIRCEP.123.012363. PubMed PMID: 38344811.
  19. Recco DP, Kneier NE, Earley PD, Kizilski SB, Hammer PE, Hoganson DM. Fiberscope-Based Measurement of Coaptation Height for Intraoperative Assessment of Mitral Valve Repair. World J Pediatr Congenit Heart Surg. 2024:21501351231221459. Epub 20240207. doi: 10.1177/21501351231221459. PubMed PMID: 38327093.
  20. Sengupta A, Nathan M. Utility of Mechanical Ventilation Duration as a Pediatric Cardiac Intensive Care Unit Quality Metric: Are We There Yet? Ann Thorac Surg. 2024;117(2):447-8. Epub 20221212. doi: 10.1016/j.athoracsur.2022.12.009. PubMed PMID: 36521523.
  21. Shanmugam NRS, Kulandaisamy A, Veluraja K, Gromiha MM. CarbDisMut: database on neutral and disease-causing mutations in human carbohydrate-binding proteins. Glycobiology. 2024. Epub 20240209. doi: 10.1093/glycob/cwae011. PubMed PMID: 38335248.
  22. Shibbani K, Abdulkarim A, Budts W, Roos-Hesselink J, Muller J, Shafer K, Porayette P, Zaidi A, Kreutzer J, Alsaied T. Participation in Competitive Sports by Patients With Congenital Heart Disease: AHA/ACC and EAPC/ESC/AEPC Guidelines Comparison. J Am Coll Cardiol. 2024;83(7):772-82. doi: 10.1016/j.jacc.2023.10.037. PubMed PMID: 38355248.
  23. Wu S, Yang P, Geng Z, Li Y, Guo Z, Lou Y, Zhang S, Xiong J, Hu H, Guo X, Pu WT, Zhang Y, Zhu D, Zhang B. Base editing effectively prevents early-onset severe cardiomyopathy in Mybpc3 mutant mice. Cell Res. 2024. Epub 20240209. doi: 10.1038/s41422-024-00930-7. PubMed PMID: 38337022.
  24. Xiao F, Zhang X, Morton SU, Kim SW, Fan Y, Gorham JM, Zhang H, Berkson PJ, Mazumdar N, Cao Y, Chen J, Hagen J, Liu X, Zhou P, Richter F, Shen Y, Ward T, Gelb BD, Seidman JG, Seidman CE, Pu WT. Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease. Nat Genet. 2024. Epub 20240220. doi: 10.1038/s41588-024-01669-y. PubMed PMID: 38378865.
  25. Zaidi AH, Saleeb SF, Gurvitz M, Bucholz E, Gauvreau K, Jenkins KJ, de Ferranti SD. Social Determinants of Health Including Child Opportunity Index Leading to Gaps in Care for Patients With Significant Congenital Heart Disease. J Am Heart Assoc. 2024;13(4):e028883. Epub 20240214. doi: 10.1161/JAHA.122.028883. PubMed PMID: 38353239.
  26. Zhang M, Wu K, Zhang W, Lin X, Cao Q, Zhang L, Chen K. The therapeutic potential of targeting the CHD protein family in cancer. Pharmacol Ther. 2024;256:108610. Epub 20240215. doi: 10.1016/j.pharmthera.2024.108610. PubMed PMID: 38367868.
  27. Zhang Y, de Ferranti SD, Moran AE. Genetic testing for familial hypercholesterolemia. Curr Opin Lipidol. 2024. Epub 20240201. doi: 10.1097/MOL.0000000000000925. PubMed PMID: 38299384.
January 2024
  1. Armenian SH, Hudson MM, Lindenfeld L, Chen S, Chow EJ, Colan S, Collier W, Su X, Marcus E, Echevarria M, Iukuridze A, Robison LL, Wong FL, Chen MH, Bhatia S. Effect of carvedilol versus placebo on cardiac function in anthracycline-exposed survivors of childhood cancer (PREVENT-HF): a randomised, controlled, phase 2b trial. Lancet Oncol. 2024;25(2):235-45. Epub 20240109. doi: 10.1016/S1470-2045(23)00637-X. PubMed PMID: 38215764.
  2. Boscamp NS, Maschietto N, Porras D. Transcatheter pulmonary valve replacement in surgically-created double-barrel right ventricular outflow tracts: A single center case-series. Catheter Cardiovasc Interv. 2024. Epub 20240111. doi: 10.1002/ccd.30954. PubMed PMID: 38204358.
  3. Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, Shen KM, Khan Z, Theisen JWM, Yang XH, Ikegami K, Efimov IR, Pu WT, Weber CR, McNally EM, Svensson EC, Moskowitz IP. A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation. 2024. Epub 20240108. doi: 10.1161/CIRCULATIONAHA.123.066804. PubMed PMID: 38189150.
  4. Brown SR, Assy J, Anderson MP, Thiagarajan RR, Brogan TV. Outcomes After Respiratory Extracorporeal Life Support in Teens and Young Adults: An Extracorporeal Life Support Organization Registry Analysis. Crit Care Med. 2024;52(1):11-9. Epub 20230905. doi: 10.1097/CCM.0000000000006049. PubMed PMID: 38095517.
  5. Day-Lewis M, Berbert L, Baker A, Dionne A, Newburger JW, Son MBF. Updated Case Definition of MIS-C and Implications for Clinical Care. Pediatrics. 2024;153(2). doi: 10.1542/peds.2023-063259. PubMed PMID: 38204335.
  6. Doulamis IP, Tzani A. Can mitochondria brown the lower-limb adipocytes? Mol Ther Methods Clin Dev. 2024;32(1):101181. Epub 20240105. doi: 10.1016/j.omtm.2023.101181. PubMed PMID: 38282897; PubMed Central PMCID: PMCPMC10818182.
  7. Jurow K, Gauvreau K, Maschietto N, Prakash A. Growth of the right ventricular outflow tract in repaired tetralogy of Fallot: A longitudinal CMR study. J Cardiovasc Magn Reson. 2024;26(1):100002. Epub 20240110. doi: 10.1016/j.jocmr.2023.100002. PubMed PMID: 38211659.
  8. Mandell JG, Romanowicz J, Loke YH, Ikeda N, Pena E, Siddiqi U, Hibino N, Alexander ME, Powell AJ, Olivieri LJ. Aortic arch shape after arch repair predicts exercise capacity: a multicentre analysis. Eur Heart J Open. 2024;4(1):oead138. Epub 20231226. doi: 10.1093/ehjopen/oead138. PubMed PMID: 38223303; PubMed Central PMCID: PMCPMC10786438.
  9. Mills KI, Albert BD, Bechard LJ, Chu S, Duggan CP, Kaza A, Rakoff-Nahoum S, Sleeper LA, Newburger JW, Priebe GP, Mehta NM. Stress Ulcer Prophylaxis Versus Placebo-A Blinded Pilot Randomized Controlled Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease. Pediatr Crit Care Med. 2024;25(2):118-27. Epub 20240119. doi: 10.1097/PCC.0000000000003384. PubMed PMID: 38240536; PubMed Central PMCID: PMCPMC10829532.
  10. Moynihan KM, Taylor LS, Siegel B, Nassar N, Lelkes E, Morrison W. "Death as the One Great Certainty": ethical implications of children with irreversible cardiorespiratory failure and dependence on extracorporeal membrane oxygenation. Front Pediatr. 2023;11:1325207. Epub 20240111. doi: 10.3389/fped.2023.1325207. PubMed PMID: 38274466; PubMed Central PMCID: PMCPMC10808631.
  11. Olsen FJ, Biering-Sorensen T, Lunze F, Hegde SM, Colan SD, Ehrbar R, Massaro J, Ferraro AM, Harrild DM, Kleinman ME, Gordon LB, Prakash A. Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome. J Am Heart Assoc. 2024:e031470. Epub 20240131. doi: 10.1161/JAHA.123.031470. PubMed PMID: 38293952.
  12. Park C, Singh M, Saeed MY, Nguyen CT, Roche ET. Biorobotic hybrid heart as a benchtop cardiac mitral valve simulator. Device. 2024;2(1). Epub 20240110. doi: 10.1016/j.device.2023.100217. PubMed PMID: 38312504; PubMed Central PMCID: PMCPMC10836162.
  13. Quinn BP, Gunnelson LC, Kotin SG, Gauvreau K, Yeh MJ, Hasan B, Lozier J, Barry OM, Shahanavaz S, Batlivala SP, Salavitabar A, Foerster S, Goldstein B, Divekar A, Holzer R, Nicholson GT, O'Byrne ML, Whiteside W, Bergersen L. Catheterization for Congenital Heart Disease Adjustment for Risk Method II. Circ Cardiovasc Interv. 2024:e012834. Epub 20240123. doi: 10.1161/CIRCINTERVENTIONS.123.012834. PubMed PMID: 38258562.
  14. Ramachandran PS, Okaty BW, Riehs M, Wapniarski A, Hershey D, Harb H, Zia M, Haas EA, Alexandrescu S, Sleeper LA, Vargas SO, Gorman MP, Campman S, Mena OJ, Levert K, Hyland K, Goldstein RD, Wilson MR, Haynes RL. Multiomic Analysis of Neuroinflammation and Occult Infection in Sudden Infant Death Syndrome. JAMA Neurol. 2024. Epub 20240129. doi: 10.1001/jamaneurol.2023.5387. PubMed PMID: 38285456; PubMed Central PMCID: PMCPMC10825787.
  15. Ryan JR, Ghosh R, Sturgeon G, Ali A, Arribas E, Braden E, Chadalavada S, Chepelev L, Decker S, Huang YH, Ionita C, Lee J, Liacouras P, Parthasarathy J, Ravi P, Sandelier M, Sommer K, Wake N, Rybicki F, Ballard D. Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: pediatric congenital heart disease conditions. 3D Print Med. 2024;10(1):3. Epub 20240129. doi: 10.1186/s41205-023-00199-3. PubMed PMID: 38282094; PubMed Central PMCID: PMCPMC10823658.
  16. Sachdeva R, Armstrong AK, Arnaout R, Grosse-Wortmann L, Han BK, Mertens L, Moore RA, Olivieri LJ, Parthiban A, Powell AJ. Novel Techniques in Imaging Congenital Heart Disease: JACC Scientific Statement. J Am Coll Cardiol. 2024;83(1):63-81. doi: 10.1016/j.jacc.2023.10.025. PubMed PMID: 38171712.
  17. Samsel C, Reichman JR, Barreto JA, Brown DW, Hummel K, Sleeper LA, Blume ED. The experience of fathers of children hospitalised with advanced heart disease. Cardiol Young. 2024:1-5. Epub 20240110. doi: 10.1017/S1047951123004390. PubMed PMID: 38196389.
  18. Sengupta A, Carreon CK, Gauvreau K, Lee JM, Sanders SP, Colan SD, Del Nido PJ, Mayer JE, Jr., Nathan M. Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries. J Am Coll Cardiol. 2024;83(4):516-27. Epub 20231106. doi: 10.1016/j.jacc.2023.10.023. PubMed PMID: 37939977.
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